Hydroxyl radical generation via photoreduction of a simple pyridine N-oxide by an NADH analogue.
نویسندگان
چکیده
Photoreduction of pyridine N-oxide, which has a key structure of antitumor agents for hypoxic solid tumors, by 1-benzyl-1,4-dihydronicotinamide in deaerated aprotic media resulted in generation of hydroxyl radical, leading to the oxidation of salicylic acid to 2,3- and 2,5-dihydroxybenzoic acids, and catechol.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 3 18 شماره
صفحات -
تاریخ انتشار 2005